It sounds unexpected: salmon DNA in skincare. Yet PDRN has become a talking point in the search for smoother-looking texture, improved hydration and better overall skin quality.
At LONGEVIE, we look beyond an ingredient’s popularity. We consider the complete formulation, how it is intended to be used and whether it fits your skin’s needs.
Our Advanced protocol includes a professional preparation containing both PDRN and exosomes, alongside personalised AXION microneedling where appropriate.
What is PDRN?
PDRN stands for polydeoxyribonucleotide: a preparation of purified DNA fragments. Many established preparations are derived from salmonid fish, which explains the term “salmon DNA”, or “Lachs-DNA” in German.
PDRN has been investigated for its role in tissue-repair pathways. Researchers are also exploring its use in topical skincare, including specific formulations aimed at improving visible signs of skin ageing.
What do exosomes add to the conversation?
Exosomes are tiny extracellular vesicles involved in communication between cells. They can carry biological molecules, which is why researchers are investigating their potential in skin care.
Clinical research has explored certain exosome-containing preparations used with microneedling, with promising findings for skin texture, elasticity and the appearance of wrinkles.
Why consider microneedling alongside a professional formulation?
Microneedling creates controlled, tiny punctures in the skin. Professional treatment plans may use it to address concerns such as uneven texture and the appearance of fine lines or certain scars.
How does LONGEVIE personalise Advanced care?
We begin with consultation and assessment. We discuss your priorities, current skincare, previous procedures and relevant health information before considering treatment.
Our Advanced approach may combine AXION microneedling with the professional preparation containing both PDRN and exosomes, according to suitability and the preparation’s intended use.
What about creams and home care?
A professional session and a home-care product have different roles. Do not assume that a PDRN or exosome cream can reproduce an in-studio procedure, or that it is suitable immediately afterwards.
Follow your individual aftercare instructions, including when to cleanse, restart active products, wear makeup and return to your usual activities. Your ongoing routine should be manageable and appropriate for your skin’s recovery.
Find out whether Advanced care is right for you
At LONGEVIE Skin & Body Lab in Cham, consultation and multispectral skin imaging help us understand your skin’s visible condition and follow changes over time. Imaging supports cosmetic assessment; it does not replace medical diagnosis.
Bring the products you already use and tell us about any recent treatments. Together, we can discuss whether Advanced microneedling belongs in your plan and how your home care can support it.
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